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Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian Tube

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.28.119933Source: DataRank Database

Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian Tube is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.436. It has been cited 6 times, with 5 citing works in its 1-hop citation network.

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0.436DataRank · unranked

Scored on demand from live citation data

Open Access6 citations · 5 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)OA: greenTopics (66)IDs (PubMed, OpenAlex)SDGs (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 67%Citation Network 33%

Base Score Contribution

0.292

From this paper's citation signal

Citation Network Contribution

0.144

From 5 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 5 citers.

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Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified by scRNA-seq
bioRxiv (Cold Spring Harbor Laboratory)20214 citations37 referencesContributes 0.043
From a Passive Conduit to Highly Dynamic Organ. What are the Roles of Uterine Tube Epithelium in Reproduction?
Physiological Research202213 citations63 referencesContributes 0.042
Motile cilia: Key developmental and functional roles in reproductive systems
Andrology20258 citations184 referencesContributes 0.012
Impact of BRCA mutations, age, surgical indication, and hormone status on the molecular phenotype of the human Fallopian tube
Nature Communications20252 citations104 referencesContributes 0.011

Authors (18)

Xianzhi Lin ORCID,Forough Abbasi ORCID,Robbin Nameki ORCID,Marcela Haro,Claire Olingy ORCID

Live enrichment

PubMed:19965766 OpenAlex:https://openalex.org/W3029698122

National Institutes of Health

Grant: 5R01CA211707-04

Functional Effects of Ovarian Cancer Risk Variants

National Institutes of Health

Grant: 5T32GM118288-04

Graduate Program in Biomedical Sciences and Translational Medicine

National Institutes of Health

Grant: 3UL1TR001881-01S2

UCLA Clinical Translational Science Institute

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/05/30/2020.05.28.119933.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.05.28.119933

repositoryhttps://doi.org/10.1101/2020.05.28.119933

https://doi.org/10.1016/j.celrep.2021.108978

Fields of Study

Ovarian cancer diagnosis and treatmentSingle-cell and spatial transcriptomicsCancer-related molecular mechanisms research0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

BiologyFallopian tubeTranscriptomePopulationSerous fluidCarcinogenesisEpitheliumCell biologyMesenchymal stem cellCell typeCellGeneGene expressionGeneticsMedicineAnatomyMedical PhysiologySOXF Transcription Factors2.1 Biological and endogenous factorsBiology (General)transcription factorCancerTumorLeiomyomaCell DifferentiationBiological SciencesMiddle AgedOvarian CancerGene Expression Regulation, NeoplasticFemalesecretory epithelial cellsSingle-Cell AnalysisSignal TransductionAdultEpithelial-Mesenchymal TransitionRUNX3QH301-705.5Endometriosis610Cell LinePAX8 Transcription FactorRare DiseasesClinical ResearchCell Line, Tumor616scRNA-seqciliated epithelial cellsHumansSOX17Fallopian TubesNeoplasticGene Expression ProfilingHuman GenomeEpithelial CellsmicroenvironmentPAX8Core Binding Factor Alpha 3 SubunitGene Expression RegulationWomen's HealthBiochemistry and Cell Biology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: No povertySDG 0: Good health and well-being