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Transfer learning between preclinical models and human tumors identifies conserved NK cell activation signature in anti-CTLA-4 responsive tumors

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.31.125625Source: DataRank Database

Transfer learning between preclinical models and human tumors identifies conserved NK cell activation signature in anti-CTLA-4 responsive tumors is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Enrichment:Funding (9 grants)OA: greenTopics (28)IDs (PubMed)SDGs (1)

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Authors (8)

Allison A. Fitzgerald ORCID,Michael D. Kessler ORCID,Ludmila Danilova ORCID,Elizabeth M. Jaffee ORCID,Neeha Zaidi ORCID

Live enrichment

PubMed:19910364

National Institutes of Health

Grant: 1R50CA243627-01

Comprehensive Analysis and Multi-Omics Data Integration for Cancer-Related Studies

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Grant: 1U01CA196390-01

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T cell mechanisms of immunotherapy response in pancreatic ductal adenocarcinoma

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Grant: 5R01CA184926-03

(PQB-3) Driver gene-induced inflammation in pancreatic cancer development

National Institutes of Health

Grant: 5U01CA212007-03

Integrating bioinformatics into multiscale models for hepatocellular carcinoma

National Institutes of Health

Grant: 3P30CA006973-53S2

Regional Oncology Research Center

National Institutes of Health

Grant: 5R01CA177669-05

Dynamical Models of Cetuximab Resistance in HNSCC Based on Serial Genomics Data

National Institutes of Health

Grant: 5F30CA239441-03

The Potential Role of Firboblast Activation Protein as a Natural Killer Cell Immune Checkpoint in Pancreatic Cancer

National Institutes of Health

Grant: 5P50CA062924-25

SPORE in Gastrointestinal Cancers

greenLicense: cc-by-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/03/08/2020.05.31.125625.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.05.31.125625

https://doi.org/10.1101/2020.05.31.125625

https://doi.org/10.1186/s13073-021-00944-5

https://genomemedicine.biomedcentral.com/track/pdf/10.1186/s13073-021-00944-5

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Drug Evaluation, PreclinicalQH426-470Lymphocyte ActivationModels, BiologicalMiceCell Line, TumorNeoplasmsDatabases, GeneticGeneticsAnimalsHumansCTLA-4 AntigenImmune Checkpoint InhibitorsMelanomaResearchGene Expression ProfilingRComputational BiologyPrognosisIpilimumabKiller Cells, NaturalDisease Models, AnimalGene Expression RegulationMedicineBiomarkers

Sustainable Development Goals

SDG 3: 3. Good health