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Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.22.166033Source: DataRank Database

Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Enrichment:Funding (8 grants)OA: greenTopics (34)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (38)

I‐Ting Teng ORCID,Adam S. Olia ORCID,Gabriele Cerutti ORCID,Jason Gorman ORCID,Alexandra F. Nazzari ORCID

Live enrichment

PubMed:32596696 OpenAlex:https://openalex.org/W3036036135

National Institutes of Health

Grant: 7P41GM103310-14

National Resource for Automated Molecular Microscopy

National Institutes of Health

Grant: 3DP5OD023118-05S1

Antibody display libraries for precision screening of antibody immune responses to SARS-CoV-2

National Institutes of Health

Grant: 1R21AI143407-01

Comprehensive molecular and functional analyses of anti-HIV-1 broadly neutralizing antibody repertoires

National Institutes of Health

Grant: 1R21AI144408-01

Probing antigen specificity and response of autoimmune B cells in Neuromyelitis Optica

NIH HHS

Grant: DP5 OD023118

NIGMS NIH HHS

Grant: P41 GM103310

NIAID NIH HHS

Grant: R21 AI143407

NIAID NIH HHS

Grant: R21 AI144408

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/06/23/2020.06.22.166033.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.06.22.166033

repositoryhttps://doi.org/10.1101/2020.06.22.166033

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32596696

Fields of Study

SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniques0301 basic medicine03 medical and health sciences

Keywords

EctodomainBiotinylationBiotinSpike (software development)ChemistryBiologyMolecular biologyComputational biologyBiochemistryBiophysicsReceptorComputer scienceCryoelectron MicroscopyPneumonia, ViralCOVID-19Peptidyl-Dipeptidase AAntibodies, ViralAntibodies, NeutralizingGeneral Biochemistry, Genetics and Molecular BiologyArticleAntibody SpecificityMolecular ProbesSpike Glycoprotein, CoronavirusHumansReceptors, VirusAngiotensin-Converting Enzyme 2Binding Sites, AntibodyCoronavirus InfectionsPandemics

Sustainable Development Goals

SDG 3: 3. Good health