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Increased baseline RASGRP1 signals Enhance Stem Cell Fitness during Native Hematopoiesis

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.24.169631Source: DataRank Database

Increased baseline RASGRP1 signals Enhance Stem Cell Fitness during Native Hematopoiesis is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (103)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (9)

Damià Romero–Moya ORCID,Olga Ksionda,Milana Krush ORCID,Zhaohui Gu ORCID,Marsilius Mues

Live enrichment

PubMed:19910364 OpenAlex:https://openalex.org/W3037250675

National Institutes of Health

Grant: 5R01CA187318-09

Molecular understanding of leukemic bone marrow cytokine-Ras signals and metabolic dependence

National Institutes of Health

Grant: 5P30DK063720-03

ISLET PRODUCTION FACILITY CORE

National Institutes of Health

Grant: 3P30CA021765-41S2

Cancer Center Support Grant (CCSG)

National Institutes of Health

Grant: 5R01HL120724-02

Balanced signaling cues to guide cell transitions in the blood lineage continuum

National Institutes of Health

Grant: 5R35CA197695-05

Translating genomic discoveries to improved outcomes for high risk acute leukemia

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/06/25/2020.06.24.169631.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.06.24.169631

repositoryhttps://doi.org/10.1101/2020.06.24.169631

repositoryhttps://escholarship.org/uc/item/1cm424xd

Fields of Study

Acute Lymphoblastic Leukemia researchAcute Myeloid Leukemia ResearchChronic Myeloid Leukemia Treatments0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Cancer researchKRASBiologyBone marrowHaematopoiesisLeukemiaProgenitor cellStem cellCell biologyGeneticsImmunologyGeneMutationMalePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma (mesh)DNA-Binding Proteins (mesh)Ribosomal Protein S6 Kinases (mesh)Hematopoietic Stem Cells (mesh)Regenerative MedicinePrecursor T-Cell Lymphoblastic Leukemia-LymphomaTransgenicBone Marrow (mesh)Leukemic (mesh)Regenerative Medicine (rcdc)MiceStem Cell Research - Nonembryonic - Human1103 Clinical Sciences (for)Guanine Nucleotide Exchange Factors (mesh)Childhood Leukemia (rcdc)Animals (mesh)Guanine Nucleotide Exchange Factors32 Biomedical and Clinical Sciences (for-2020)Stem Cell Research - Nonembryonic - Human (rcdc)Male (mesh)3101 Biochemistry and cell biology (for-2020)ChildCells, CulturedCancerLeukemicCancer (rcdc)Humans (mesh)CulturedGene Expression Regulation, LeukemicTOR Serine-Threonine KinasesHematopoietic Stem Cell TransplantationMice (mesh)HematologyTOR Serine-Threonine Kinases (mesh)1112 Oncology and Carcinogenesis (for)Pediatric Cancer (rcdc)DNA-Binding ProteinsStem Cell Research - Nonembryonic - Non-HumanStem Cell Research - Nonembryonic - Non-Human (rcdc)FemaleCultured (mesh)Signal TransductionHematopoietic Stem Cell Transplantation (mesh)CellsClinical SciencesOncology and CarcinogenesisPrimary Cell CultureChild (mesh)Transgenic (mesh)Primary Cell Culture (mesh)Mice, TransgenicHematopoiesis (mesh)ArticleRare Diseases (rcdc)Colony-Forming Units AssayRare Diseases3211 Oncology and carcinogenesis (for-2020)AnimalsHumansOncology & CarcinogenesisPediatric (rcdc)Colony-Forming Units Assay (mesh)Animal (mesh)1.1 Normal biological development and functioning (hrcs-rac)Transplantation ChimeraHematology (rcdc)Transplantation Chimera (mesh)31 Biological Sciences (for-2020)AnimalRibosomal Protein S6 Kinases2.1 Biological and endogenous factors (hrcs-rac)Cancer (hrcs-hc)Stem Cell ResearchHematopoietic Stem CellsStem Cell Research (rcdc)HematopoiesisDisease Models, AnimalGene Expression RegulationOncology & Carcinogenesis (science-metrix)Female (mesh)Disease ModelsSignal Transduction (mesh)3201 Cardiovascular Medicine and Haematology (for-2020)

Sustainable Development Goals

SDG 0: Good health and well-being