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6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.01.183020Source: DataRank Database

6-Thioguanine blocks SARS-CoV-2 replication by inhibition of PLpro protease activities is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 36 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access36 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)OA: greenTopics (28)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Yi-Chieh Perng ORCID,Xu Zhao ORCID,Larissa A. Canadeo,Houda Harastani ORCID,Tamarand L. Darling ORCID

Live enrichment

PubMed:32637945 OpenAlex:https://openalex.org/W3040065139

National Institutes of Health

Grant: 1UL1TR002345-01

Washington University Institute of Clinical and Translational Sciences

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/07/02/2020.07.01.183020.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.07.01.183020

repositoryhttps://doi.org/10.1101/2020.07.01.183020

repositoryhttps://pubmed.ncbi.nlm.nih.gov/32637945

Fields of Study

interferon and immune responsesSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies0301 basic medicine03 medical and health sciences

Keywords

ISG15ProteaseVirologyVero cellCoronavirusViral replicationCleavage (geology)Antiviral drugDrugSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ChemistryCoronavirus disease 2019 (COVID-19)BiologyEnzymeUbiquitinBiochemistryVirusGenePharmacologyMedicineInfectious disease (medical specialty)DiseaseArticle

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being