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Autophagy Compensates for Lkb1 Loss to Maintain Adult Mice Homeostasis and Survival

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.26.268003Source: DataRank Database

Autophagy Compensates for Lkb1 Loss to Maintain Adult Mice Homeostasis and Survival is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (41)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (6)

Vrushank Bhatt ORCID,Zhixian Hu ORCID,Sajid Fahumy,Xuefei Luo,Jessie Yanxiang Guo ORCID

Live enrichment

PubMed:23304386 OpenAlex:https://openalex.org/W3081181146

National Institutes of Health

Grant: 3P30CA072720-07S2

CANCER CENTER SUPPORT GRANT

National Institutes of Health

Grant: 5K22CA190521-03

The role of autophagy in Kras-driven lung cancer

National Institutes of Health

Grant: 5R01CA237347-06

Elucidate the mechanism of autophagy in supporting Lkb1-deficient lung tumorigenesis and metastasis

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/08/26/2020.08.26.268003.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.08.26.268003

repositoryhttps://doi.org/10.1101/2020.08.26.268003

https://doi.org/10.7554/elife.62377

Fields of Study

Autophagy in Disease and TherapyPancreatic function and diabetesMetabolism, Diabetes, and Cancer0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

AutophagyCell biologyHomeostasisBiologyDownregulation and upregulationULK1KinaseProgrammed cell deathOrganelleProtein kinase AGeneApoptosisBiochemistryp53LKB1SurvivalQH301-705.5ScienceAMP-Activated Protein KinasesProtein Serine-Threonine KinasesAutophagy-Related Protein 7Miceintestinal epithelium barrierAnimalsBiology (General)Intestinal MucosaQREpithelial Cellshost homeostasisGene Expression RegulationMedicineTumor Suppressor Protein p53Atg7Gene Deletion

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 0: Affordable and clean energy