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High-content analysis and Kinetic Image Cytometry identify toxic and epigenotoxic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.09.05.284422Source: DataRank Database

High-content analysis and Kinetic Image Cytometry identify toxic and epigenotoxic effects of HIV antiretrovirals on human iPSC-neurons and primary neural precursor cells is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Enrichment:Funding (3 grants)OA: greenTopics (23)IDs (PubMed)SDGs (1)

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Authors (11)

Soneela Ankam,Chen Farhy ORCID,Lorenzo Fiengo,Ranor C.B. Basa ORCID,Kara L. Gordon ORCID

Live enrichment

PubMed:19767382

National Institutes of Health

Grant: 1R41MH119621-01A1

The Microscopic Imaging of Epigenetic Landscape- NeuroDevelopment (MIEL-ND) assay: a high throughput platform to screen compounds for neurodevelopmental effects

National Institutes of Health

Grant: 5R44ES026268-03

Assay of chemicals for Parkinson's toxicity in human iPSC-derived neurons

National Institutes of Health

Grant: 1R43AG062012-01

The Alzheimer's Therapeutics Screening Assay: a high-throughput drug-discovery platform utilizing neurons and microglia derived from human induced pluripotent stem cells and Kinetic Image Cytometry

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/01/11/2020.09.05.284422.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.09.05.284422

https://doi.org/10.1016/j.vascn.2022.107157

https://doi.org/10.1101/2020.09.05.284422

https://pubmed.ncbi.nlm.nih.gov/35143957

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences0302 clinical medicine

Keywords

AdultNeuronsHuman induced pluripotent stem cell-derived glutamatergic neurons571HIV-associated neurocognitive disorderInduced Pluripotent Stem CellsHigh content analysisHIV InfectionsKinetic image cytometryAdult and Continuing EducationEpigenetic regulationEpigenesis, GeneticHIV antiretroviralsNeural Stem CellsHuman neural precursor cellsCalcium transientsNeuritesSynapsesHumansImage Cytometry

Sustainable Development Goals

SDG 3: 3. Good health