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Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.13.338384Source: DataRank Database

Effects of NT5C2 germline variants on 6-mecaptopurine metabolism in children with acute lymphoblastic leukemia is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Enrichment:Funding (3 grants)OA: greenTopics (23)IDs (PubMed)SDGs (1)

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Authors (17)

Wenjian Yang ORCID,Takaya Moriyama ORCID,Chengcheng Liu ORCID,Colton Smith ORCID,Wentao Yang ORCID

Live enrichment

PubMed:21097893

National Institutes of Health

Grant: 5P50GM115279-03

Center for Precision Medicine in Leukemia (CPML)

National Institutes of Health

Grant: 1R01GM118578-01A1

Genetics-guided Individualization of Thiopurine Therapy

National Institutes of Health

Grant: 5R01CA096670-05

Ethnic Differences in Survival after Childhood ALL

greenLicense: Wiley Online Library User Agreement

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/10/14/2020.10.13.338384.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.10.13.338384

https://doi.org/10.1002/cpt.2095

https://doi.org/10.1101/2020.10.13.338384

https://pubmed.ncbi.nlm.nih.gov/33124053

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

MaleAntimetabolites, AntineoplasticErythrocytesAdolescentMercaptopurineMutation, MissensePolymorphism, Single NucleotideLinkage DisequilibriumCohort StudiesGene Expression Regulation, NeoplasticChild, PreschoolMultigene FamilyMultivariate AnalysisHumansFemaleChild5'-NucleotidaseAllelesGerm-Line MutationGenome-Wide Association Study

Sustainable Development Goals

SDG 3: 3. Good health