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Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.23.352872Source: DataRank Database

Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 7 times.

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Open Access7 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (54)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (15)

Choya Yoon,Lucas D. Huffman ORCID,Patrick C. Duncker ORCID,Rafi Kohen ORCID,Ryan Passino ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3093851682

National Institutes of Health

Grant: 5T32NS007222-27

Training in Clinical and Basic Neuroscience

National Institutes of Health

Grant: 7R01EY029159-03

A novel inflammatory cell with neuroprotective and neuroregenerative properties

National Institutes of Health

Grant: 7R01EY028350-03

Immune mediated regeneration of retinal ganglion cell axons following optic nerve trauma

National Institutes of Health

Grant: 5T32GM113900-02

Training Program in Translational Research

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/10/24/2020.10.23.352872.1.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.10.23.352872

repositoryhttps://doi.org/10.1101/2020.10.23.352872

https://doi.org/10.7554/elife.60223

Fields of Study

Nerve injury and regenerationNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

EfferocytosisWallerian degenerationSciatic nerveInflammationNerve injuryLesionAxotomyMedicineMacrophageRegeneration (biology)PathologySciatic nerve injuryCell biologyImmunologyAnatomyBiologyAnesthesiaIn vitroMalescRNA sequencingQH301-705.5ScienceNeuronal OutgrowthApoptosisMonocytesCytokine Receptor Common beta SubunitPeripheral Nerve InjuriesGanglia, SpinalLeukocytesAnimalsGene Regulatory NetworksBiology (General)Cells, CulturedMice, Knockoutconditioning lesionMacrophagesQaxon regenerationRdorsal root gangliaGranulocyte-Macrophage Colony-Stimulating FactorNerve RegenerationMice, Inbred C57BLDisease Models, AnimalGene Expression RegulationFemaleInflammation MediatorsNeuroscience

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being