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Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

medRxiv(2020)10.1101/2020.10.25.20219188Source: DataRank Database

Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder is a research paper published in medRxiv (2020). On theSindex it has a DataRank of 0. It has been cited 5 times.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (28)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (10)

Di Liu ORCID,Chuntao Zhao ORCID,Bowen Feng,Wenjin Lu ORCID,Xiaohan Yang ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3093971864

National Institutes of Health

Grant: 5R01AG017917-20

Epidemiologic Study of Neural Reserve and Neurobiology of Aging

National Institutes of Health

Grant: 3U01AG061356-02S1

Multi-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targets

National Institutes of Health

Grant: 1P30AG010161-01

SHORT-TERM STABILITY OF CLINICAL TESTS

National Institutes of Health

Grant: 1RF1AG064312-01

Integrative Motor Activity Biomarker for the Risk of Alzheimer's Risk

National Institutes of Health

Grant: 5R01AG036042-05

Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences

National Institutes of Health

Grant: 5R01AG015819-07

Risk Factors, Pathology, and Clinical Expressions of AD

greenLicense: CC BY

repositoryhttps://www.medrxiv.org/content/medrxiv/early/2020/10/27/2020.10.25.20219188.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.10.25.20219188

repositoryhttps://doi.org/10.1101/2020.10.25.20219188

https://doi.org/10.1038/s41398-021-01348-0

Fields of Study

Tryptophan and brain disordersGenetic Associations and EpidemiologyBioinformatics and Genomic Networks0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Mendelian randomizationExpression quantitative trait lociMajor depressive disorderGenome-wide association studyBiologyGeneticsQuantitative trait locusGeneGenetic associationComputational biologySingle-nucleotide polymorphismGenetic variantsNeuroscienceGenotypeQuantitative Trait LociNeurosciences. Biological psychiatry. NeuropsychiatryMendelian Randomization AnalysisPolymorphism, Single NucleotideArticleHumansGenetic Predisposition to DiseaseRC321-571

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being