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Activating mGlu 3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.27.356196Source: DataRank Database

Activating mGlu 3 metabotropic glutamate receptors rescues schizophrenia-like cognitive deficits through metaplastic adaptations within the hippocampus is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (9 grants)OA: greenTopics (28)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (10)

Branden J. Stansley ORCID,Zixiu Xiang ORCID,Weilun Qian,Rocco G. Gogliotti ORCID,Ferdinando Nicoletti ORCID

Live enrichment

PubMed:23304386 OpenAlex:https://openalex.org/W3095319344

National Institutes of Health

Grant: 5P60DK020593-25

Diabetes Research and Training Center

National Institutes of Health

Grant: 7R01MH062646-04

REGULATION OF SIGNALING BY MGLUR5

National Institutes of Health

Grant: 5K99AA027806-02

Sex differences in fast-spiking interneurons promote AUD-related PFC dysfunction: remediation by modulating mGlu1 and mGlu5

National Institutes of Health

Grant: 1U24DK059637-01

CORE--METABOLIC PATHOPHYSIOLOGY

National Institutes of Health

Grant: 3P30CA068485-23S2

Cancer Center Support Grant

National Institutes of Health

Grant: 3F32MH111124-01S1

The therapeutic potential of mGlu3 modulation in MeCP2-related disorders

National Institutes of Health

Grant: 1P30DK058404-01A1

CORE--MICROARRAY

National Institutes of Health

Grant: 5R37NS031373-22

Functions of Metabotropic Glutamate Receptor Subtypes

National Institutes of Health

Grant: 1K01MH112983-01A1

Normalizing E:I imbalance in Rett Syndrome by Modulation of Late Response Genes

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/10/27/2020.10.27.356196.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.10.27.356196

repositoryhttps://doi.org/10.1101/2020.10.27.356196

https://doi.org/10.1016/j.biopsych.2021.02.970

Fields of Study

Neuroscience and Neuropharmacology ResearchBiochemical Analysis and Sensing TechniquesMemory and Neural Mechanisms0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

NeuroscienceMetabotropic glutamate receptorMetabotropic receptorHippocampal formationLong-term depressionMetabotropic glutamate receptor 5Synaptic plasticitySchizophrenia (object-oriented programming)HippocampusGlutamate receptorPsychologyBiologyReceptorAMPA receptorPsychiatryMiceCognitionLong-Term PotentiationSchizophreniaAnimalsReceptors, Metabotropic Glutamatecognition; hippocampus; mglu3; mglu5; schizophrenia; synaptic plasticity

Sustainable Development Goals

SDG 3: 3. Good health