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The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.11.24.389627Source: DataRank Database

The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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Enrichment:Funding (7 grants)OA: greenTopics (37)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (9)

Wiebke Obermann,Nadja Karl ORCID,Hans‐Guido Wendel ORCID,Gaspar Taroncher‐Oldenburg ORCID,Stephan Pleschka ORCID

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W3109823724

National Institutes of Health

Grant: 5P50CA192937-02

MSK SPORE in Lymphoma

National Institutes of Health

Grant: 5R01CA207217-03

Exploring oncogenic translation programs in cancer

National Institutes of Health

Grant: 5R35CA252982-05

Towards targeting the lymphoma microenvironment

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

National Institutes of Health

Grant: 2P30CA008748-43

MOUSE GENETICS

National Institutes of Health

Grant: 1R01CA183876-01

Towards The Chemotherapy-Free Treatment of Follicular Lymphoma

National Institutes of Health

Grant: 5P50CA217694-04

SPORE in Soft Tissue Sarcoma

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/11/25/2020.11.24.389627.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.11.24.389627

repositoryhttps://doi.org/10.1101/2020.11.24.389627

https://doi.org/10.1016/j.antiviral.2021.105012

Fields of Study

Plant Virus Research StudiesSARS-CoV-2 and COVID-19 ResearchAnimal Virus Infections Studies0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

VirologyViral replicationEx vivoVero cellBiologyCoronavirusIn vivoIn vitroVirusMedicineCoronavirus disease 2019 (COVID-19)Infectious disease (medical specialty)DiseaseBiochemistryPharmacologySARS-CoV-2BronchiRespiratory MucosaViral LoadHydroxamic AcidsVirus ReplicationAntiviral AgentsArticleChlorocebus aethiopsEukaryotic Initiation Factor-4AAnimalsHumansViral Replication CompartmentsVero CellsCells, CulturedBenzofurans

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being