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Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4 + T cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.04.412056Source: DataRank Database

Granzyme B prevents aberrant IL-17 production and intestinal pathogenicity in CD4 + T cells is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (43)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (8)

Michael J. Greer,Kathleen G. McClanahan ORCID,Ali Nazmi ORCID,M. Blanca Piazuelo ORCID,Kshipra Singh

Live enrichment

PubMed:23304386 OpenAlex:https://openalex.org/W3168651323

National Institutes of Health

Grant: 1U24DK059637-01

CORE--METABOLIC PATHOPHYSIOLOGY

National Institutes of Health

Grant: 5T32GM008554-22

Cellular, Biochemical and Molecular Sciences Training Program

National Institutes of Health

Grant: 1T32DK007673-01A1

GASTROENTEROLOGY

National Institutes of Health

Grant: 3P30DK058404-17S1

MOLECULAR AND CELLULAR BASIS FOR DIGESTIVE DISEASES

National Institutes of Health

Grant: 5R01DK111671-03

Control of lymphocyte homeostasis by iCD8a cells and osteopontin

National Institutes of Health

Grant: 3P30CA068485-23S2

Cancer Center Support Grant

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/06/17/2020.12.04.412056.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.12.04.412056

repositoryhttps://doi.org/10.1101/2020.12.04.412056

https://doi.org/10.1038/s41385-021-00427-1

Fields of Study

T-cell and B-cell ImmunologyImmunodeficiency and Autoimmune DisordersImmune Cell Function and Interaction0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Granzyme BGranzymeCytotoxic T cellGranzyme ABiologyInterleukin 21Adoptive cell transferT cellImmune systemCD8Cell biologyImmunologyMolecular biologyPerforinIn vitroBiochemistryCD4-Positive T-LymphocytesMaleMice, KnockoutCell TransplantationGene Expression ProfilingInterleukin-17Cell DifferentiationMice, TransgenicLymphocyte ActivationArticleGranzymesImmunophenotypingMiceImmune ReconstitutionGene Expression RegulationAnimalsCytokinesFemaleDisease SusceptibilityIntraepithelial LymphocytesBiomarkers

Sustainable Development Goals

SDG 3: 3. Good health