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Structure-guided microbial targeting of antistaphylococcal prodrugs

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.15.408237Source: DataRank Database

Structure-guided microbial targeting of antistaphylococcal prodrugs is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2020). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (40)IDs (PubMed, OpenAlex)SDGs (2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Ishaan T. Shah,Jayda Hatten,Yasaman Barekatain ORCID,Elizabeth A. Mueller ORCID,Ahmed M. Moustafa ORCID

Live enrichment

PubMed:19910364 OpenAlex:https://openalex.org/W3110994568

National Institutes of Health

Grant: 7R01AI103280-08

FOSMIDOMYCIN RESISTANCE IN PLASMODIUM FALCIPARUM

National Institutes of Health

Grant: 5R21AI123808-02

TARGETING ISPC TO TREAT MALARIA

National Institutes of Health

Grant: 3UL1RR024992-03S4

Washington University Institute of Clinical and Translational Sciences (UL1)

National Institutes of Health

Grant: 5R21AI130584-02

SELECTIVE INHIBITION OF THE P. FALCIPARUM GLUCOSE TRANSPORTER PFHT

National Institutes of Health

Grant: 1R15GM110641-01A1

Investigation of mycobacterial hydrolases and their role in lipolysis.

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2020/12/15/2020.12.15.408237.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.12.15.408237

repositoryhttps://doi.org/10.1101/2020.12.15.408237

repositoryhttps://digitalcommons.wustl.edu/open_access_pubs/10524

Fields of Study

RNA and protein synthesis mechanismsClick Chemistry and ApplicationsChemical Synthesis and Analysis0301 basic medicine03 medical and health sciences

Keywords

ProdrugEsteraseChemistryHydrolysisEster hydrolysisAntibioticsSubstrate specificitySubstrate (aquarium)EnzymeBacteriaCombinatorial chemistryBiochemistryDrugBiologyPharmacologyStaphylococcus aureusQH301-705.5ScienceStaphylococcusdrug discoveryCarboxylesteraseMiceBacterial ProteinsBiochemistry and Chemical BiologyAnimalsHumansProdrugsBiology (General)QREsterasesEstersAnti-Bacterial AgentsantibacterialMedicine

Sustainable Development Goals

SDG 3: 3. Good healthSDG 13: 13. Climate action