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Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2020.12.31.424987Source: DataRank Database

Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 26 times.

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bioproject gen emdb pdb

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Enrichment:Funding (4 grants)OA: greenTopics (44)Linked Datasets (2)DataCite Reuse (2)IDs (PubMed, OpenAlex)Annotations (4)SDGs (2)

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Authors (34)

Gabriele Cerutti ORCID,Ahmed S. Fahad ORCID,Chen‐Hsiang Shen ORCID,Matheus Oliveira de Souza ORCID,Phinikoula S. Katsamba ORCID

Live enrichment

PubMed:33442681 OpenAlex:https://openalex.org/W3117953267

National Institutes of Health

Grant: 1R21AI143407-01

Comprehensive molecular and functional analyses of anti-HIV-1 broadly neutralizing antibody repertoires

National Institutes of Health

Grant: 3DP5OD023118-05S1

Antibody display libraries for precision screening of antibody immune responses to SARS-CoV-2

National Institutes of Health

Grant: 5R01AI141452-04

The influence of evolutionary landscapes on protective antibody development

National Institutes of Health

Grant: 1R21AI144408-01

Probing antigen specificity and response of autoimmune B cells in Neuromyelitis Optica

greenLicense: CC BY NC ND

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/01/03/2020.12.31.424987.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2020.12.31.424987

repositoryhttps://doi.org/10.1101/2020.12.31.424987

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33442681

Fields of Study

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesMonoclonal and Polyclonal Antibodies Research0301 basic medicine03 medical and health sciences

Keywords

AntibodyImmunoglobulin light chainNeutralizationAntibody RepertoireBiologyPeptide sequenceVirologyTrimerChemistryImmunologyGeneticsGeneMaleQH301-705.5B-cellAntibodies, ViralReportChlorocebus aethiopsAnimalsHumansProtein Interaction Domains and Motifsyeast displayBiology (General)AgedB-LymphocytesBinding SitesSARS-CoV-2Cryoelectron MicroscopyAntibodies, MonoclonalCOVID-19Antibodies, NeutralizingHEK293 CellsAntibody FormationImmunoglobulin Light ChainsAngiotensin-Converting Enzyme 2Immunoglobulin Heavy Chainspublic antibodybiotechnologyProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Additional file 1 of Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment

10.6084/m9.figshare.14471586.v1figshare

Additional file 1 of Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment

10.6084/m9.figshare.14471586figshare