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7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.30.428955Source: DataRank Database

7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome · Dryad

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: greenTopics (47)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
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Accessible (1/2)

Open Access

Interoperable (2/2)

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Reusable (0/3)

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Authors (6)

Kelly M. Hines ORCID,Josi Herron,Amy Li ORCID,David W. Baggett ORCID,Libin Xu ORCID

Live enrichment

PubMed:19965766 OpenAlex:https://openalex.org/W3126854979

National Institutes of Health

Grant: 5T32GM007750-19

DRUG ACTION, METABOLISM AND KINETICS

National Institutes of Health

Grant: 5TL1TR002318-07

NRSA Training Core

National Institutes of Health

Grant: 3T32ES007032-40S1

Environmental Pathology/Toxicology Training Program

National Institutes of Health

Grant: 1R01HD092659-01

Oxysterols in SLOS Neurodevelopment: Pathological Role and Therapy

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/02/17/2021.01.30.428955.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.01.30.428955

repositoryhttps://doi.org/10.1101/2021.01.30.428955

https://doi.org/10.7554/elife.67141

Fields of Study

Cholesterol and Lipid MetabolismReceptor Mechanisms and SignalingCaveolin-1 and cellular processes0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Smith–Lemli–Opitz syndromeOxysterolTropomyosin receptor kinase BNeurogenesisMAPK/ERK pathwayEndocrinologyInternal medicineBiologyChemistryKinaseCell biologyNeurotrophic factorsReceptorCholesterolMedicineReductaseBiochemistryEnzyme7-Dehydrocholesterol reductaseOxidoreductases Acting on CH-CH Group DonorsQH301-705.5ScienceReceptors, Nerve Growth FactorAntioxidantsMiceDehydrocholesterolsReceptors, Glucocorticoidsmith-lemli-opitz syndromeglucocorticoid receptor7-dehydrocholesterolAnimalsHumanscortical developmentBiology (General)Mitogen-Activated Protein Kinase KinasesQROxysterolsDisease Models, AnimalOxidoreductasesNeuroscience

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

7-Dehydrocholesterol-derived oxysterols cause neurogenic defects in Smith-Lemli-Opitz syndrome

10.5061/dryad.zw3r2287fDryad