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CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.03.428245Source: DataRank Database

CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: greenTopics (44)IDs (PubMed, OpenAlex)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Reece Foy ORCID,Brandon L. Mouery ORCID,Robert H. Whitaker ORCID,Andrea Corno ORCID,Christos Spanos ORCID

Live enrichment

PubMed:19965766 OpenAlex:https://openalex.org/W3128744096

Wellcome Trust

Grant: 206211

Understanding the proliferation-quiescence switch using quantitative cellular biochemistry

Wellcome Trust

Grant: 203149

Core Funding for the Wellcome Trust Centre for Cell Biology

National Institutes of Health

Grant: 3R01GM083024-07S1

Replication Licensing and the Cell Cycle

Wellcome Trust

Grant: 108504

Proteomics at the Wellcome Trust Centre for Cell Biology (WTCCB) and School of Biological Sciences (SBS), Edinburgh.

National Institutes of Health

Grant: 5T32GM135128-05

NRSA in Genetics

National Institutes of Health

Grant: 4R01GM102413-04

Integrating stress MAP kinase signaling with DNA replication origin licensing

National Institutes of Health

Grant: 5T32CA009156-20

BASIC MECHANISMS OF VIRAL AND CHEMICAL CARCINOGENESIS

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/02/04/2021.02.03.428245.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.02.03.428245

repositoryhttps://doi.org/10.1101/2021.02.03.428245

repositoryhttps://discovery.dundee.ac.uk/en/publications/5d44d874-985e-4362-85aa-04ffc9f27d07

Fields of Study

Advanced Breast Cancer TherapiesCancer-related Molecular PathwaysCancer Genomics and Diagnostics0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

Cell cycle checkpointCell cycleDNA damageDNA replicationMitosisCancer researchG2-M DNA damage checkpointDNA repairBiologyCell growthCell biologyCancerDNAGenetics570senescence/dk/atira/pure/subjectarea/asjc/1300/1312CDK6replication stress610Breast NeoplasmsPalbociclibname=General Immunology and Microbiology/dk/atira/pure/subjectarea/asjc/2800/2800Cell Line, Tumorname=General Biochemistry,Genetics and Molecular Biology/dk/atira/pure/subjectarea/asjc/2400/2400Humans/dk/atira/pure/subjectarea/asjc/1300/1300G1 PhaseCyclin-Dependent Kinase 4name=Molecular BiologyArticlesCyclin-Dependent Kinase 6name=General Neurosciencecyclin-dependent kinaseFemaleCell Division

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being