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Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.14.431174Source: DataRank Database

Direct activation of endothelial cells by SARS-CoV-2 nucleocapsid protein is blocked by Simvastatin is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 13 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access13 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)OA: greenTopics (41)IDs (PubMed, OpenAlex)SDGs (2)

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Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Tianhua Lei,Parth Patel ORCID,Chi H Lee ORCID,Paula Monaghan‐Nichols,Hongbo Xin ORCID

Live enrichment

PubMed:33594363 OpenAlex:https://openalex.org/W3132848079

National Institutes of Health

Grant: 1R15AI138116-01A1

Ribonuclease-mediated control of sepsis-induced systemic inflammation

National Institutes of Health

Grant: 1R01AI150877-01

Viral and Host Determinants of Parvovirus Replication

National Institutes of Health

Grant: 5R21AI144564-02

Parvovirus B19 NS1 nickase-based high-throughput screening and structure study of the nickase

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/02/18/2021.02.14.431174.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.02.14.431174

repositoryhttps://doi.org/10.1101/2021.02.14.431174

repositoryhttps://pubmed.ncbi.nlm.nih.gov/33594363

Fields of Study

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchVitamin C and Antioxidants Research0301 basic medicine03 medical and health sciences

Keywords

SimvastatinEndothelial activationARDSPathogenesisTLR2Endothelial dysfunctionEndothelial stem cellCoagulopathyImmunologyBiologyMedicineVirologyCancer researchLungCell biologyPharmacologyInflammationImmune systemInnate immune systemIn vitroInternal medicineBiochemistryEndocrinologySARS-CoV-2NF-kappa BCOVID-19Endothelial CellsArticleToll-Like Receptor 2Virus-Cell InteractionsCell LineHuman Umbilical Vein Endothelial CellsCoronavirus Nucleocapsid ProteinsHumansMitogen-Activated Protein KinasesSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being