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Human microglia extensively reconstitute in humanized BLT mice with human interleukin-34 transgene and support HIV-1 brain infection

Insecta mundi(2021)10.1101/2021.02.18.431677Source: DataRank Database

Human microglia extensively reconstitute in humanized BLT mice with human interleukin-34 transgene and support HIV-1 brain infection is a research paper published in Insecta mundi (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (41)IDs (PubMed, OpenAlex)SDGs (2)

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Open Access

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Authors (8)

Saroj Chandra Lohani ORCID,Yilun Cheng,Tao Wang ORCID,Lili Guo ORCID,Woong‐Ki Kim ORCID

Live enrichment

PubMed:26207759 OpenAlex:https://openalex.org/W3131617939

National Institutes of Health

Grant: 1R21AI143405-01

Impact of the gut microbiome on HIV-1 rectal transmission and immunopathogenesis during ART

National Institutes of Health

Grant: 5R01AI136756-05

Next Generation Broadly Neutralizing Antibodies to Clear HIV-1 Reservoir

National Institutes of Health

Grant: 5P30MH062261-17

Chronic HIV Infection and Aging in NeuroAIDS (CHAIN) Center

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/02/18/2021.02.18.431677.full.pdf

repositoryhttps://doi.org/10.1101/2021.02.18.431677

journalhttps://digitalcommons.unl.edu/bioscifacpub/882

https://doi.org/10.3389/fimmu.2021.672415

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsHIV Research and TreatmentImmune cells in cancer0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

MicrogliaHumanized mouseBone marrowTransgeneImmunologyProgenitor cellHaematopoiesisImmune systemGenetically modified mouseBiologyStem cellCD34Cell biologyInflammationGeneinterleukin-34610HIV InfectionsMice, TransgenicMice616AnimalsHumansTransgenesHu-BLT miceInterleukinsHematopoietic Stem Cell TransplantationLife SciencesBrainCell DifferentiationRC581-607Disease Models, AnimalNOG miceHIV-1Immunologic diseases. Allergy

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being