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LCK Regulates Homologous Recombination DNA Repair Identifying a New Target for Sensitizing PARP Inhibitors in HR Proficient Ovarian Cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.03.433791Source: DataRank Database

LCK Regulates Homologous Recombination DNA Repair Identifying a New Target for Sensitizing PARP Inhibitors in HR Proficient Ovarian Cancer is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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Authors (12)

Rashmi Bharti ORCID,Chad Braley ORCID,Ravi Kumar Alluri,Emily Esakov,Katie Crean-Tate ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W3135271345

National Institutes of Health

Grant: 5R01CA222195-05

DNA Repair Pathways Choice to Regulate Therapeutic Resistance in Cancer Cells

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/03/03/2021.03.03.433791.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.03.03.433791

repositoryhttps://doi.org/10.1101/2021.03.03.433791

Fields of Study

PARP inhibition in cancer therapyDNA Repair MechanismsOvarian cancer diagnosis and treatment0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

RAD51Poly ADP ribose polymeraseCancer researchDNA repairHomologous recombinationOvarian cancerPARP inhibitorDNA damageDNA repair protein XRCC4CancerBiologyCell biologyPolymeraseDNAMolecular biologyDNA mismatch repairGenetics

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being