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A UVB-responsive common variant at chr7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor gene ( AHR )

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.25.436649Source: DataRank Database

A UVB-responsive common variant at chr7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor gene ( AHR ) is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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Enrichment:Funding (4 grants)OA: greenTopics (17)IDs (PubMed, OpenAlex)Annotations (1)SDGs (1)

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Authors (27)

Lindsey Mehl,Tongwu Zhang ORCID,Rohit Thakur ORCID,Hayley Sowards ORCID,Timothy A. Myers ORCID

Live enrichment

PubMed:26207759 OpenAlex:https://openalex.org/W3150178151

National Institutes of Health

Grant: 5R01HG010067-05

Network-based algorithms for target identification and drug repositioning from genetic associations

National Institutes of Health

Grant: 1R01CA083115-01A2

Genetic Epidermiology of Melanoma

National Health and Medical Research Council (NHMRC)

Grant: 1129822

Improving skin cancer prevention: motivating preventive behaviours using knowledge of personalised genomic risk of melanoma

National Health and Medical Research Council (NHMRC)

Grant: 1123248

Which modifiable risk factors actually cause cancer?

greenLicense: public-domain

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/03/25/2021.03.25.436649.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.03.25.436649

repositoryhttps://doi.org/10.1101/2021.03.25.436649

https://dx.doi.org/10.1101/2021.03.25.436649

Fields of Study

melanin and skin pigmentationSkin Protection and AgingCarcinogens and Genotoxicity Assessment0301 basic medicine03 medical and health sciences

Keywords

Aryl hydrocarbon receptorBiologyAlleleGenome-wide association studyLocus (genetics)Expression quantitative trait lociGeneticsGeneCancer researchTranscription factorSingle-nucleotide polymorphismGenotype

Sustainable Development Goals

SDG 3: 3. Good health

A UVB-responsive common variant at chr7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor gene ( AHR )

FAIR Checklist

Authors (27)

Funding (4 grants)

Open Access

Topics

Annotations (Europe PMC)