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Engineering single pan-specific ubiquibodies for targeted degradation of all forms of endogenous ERK protein kinase

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.16.440242Source: DataRank Database

Engineering single pan-specific ubiquibodies for targeted degradation of all forms of endogenous ERK protein kinase is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (19)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Morgan B. Ludwicki,Bunyarit Meksiriporn ORCID,Mingji Li ORCID,Tianzheng Ye ORCID,Connor Monticello

Live enrichment

PubMed:19022398 OpenAlex:https://openalex.org/W3152632416

National Institutes of Health

Grant: 5R01GM137314-03

Molecular toolkit for high content resolution of glycomes by expansionmicroscopy

National Institutes of Health

Grant: 1R21CA132223-01A2

A new technology platform for studying protein function

National Institutes of Health

Grant: 1U54CA210184-01

Center on the Physics of Cancer Metabolism

National Science Foundation

Grant: 1144153

Graduate Reserach Fellowship Program (GRFP)

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/04/17/2021.04.16.440242.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.04.16.440242

repositoryhttps://doi.org/10.1101/2021.04.16.440242

repositoryhttps://www.zora.uzh.ch/id/eprint/210315/1/Stephens_et_al_2021.pdf

Fields of Study

Protein Degradation and InhibitorsUbiquitin and proteasome pathwaysCAR-T cell therapy research0301 basic medicine03 medical and health sciences

Keywords

Ubiquitin ligaseUbiquitinProteomeProteasomeProtein degradationBiologyCell biologyAnkyrin repeatF-box proteinMAPK/ERK pathwayKinaseSkp1Computational biologyBiochemistry

Sustainable Development Goals

SDG 0: Good health and well-being