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Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.03.441837Source: DataRank Database

Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (13 grants)OA: greenTopics (38)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (21)

Scott E. Stimpson ORCID,Katherine E. Santostefano,Lina Sui ORCID,Similoluwa O. Ogundare,Brittney N. Newby ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3159961306

National Institutes of Health

Grant: 5UG3DK122638-02

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions

National Institutes of Health

Grant: 5R01DK120444-03

Improving human pluripotent stem cell derived beta cell transplantation using genetic lineage tracing.

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5UL1TR001427-08

Together: Transforming and Translating Discovery to Improve Health

National Institutes of Health

Grant: 1UC4DK104194-01

Genetic Regulation of Human Beta Cell Destruction

National Institutes of Health

Grant: 1R24GM119977-01

A Stem Cell Tactic to Promote Personalized Medicine

National Institutes of Health

Grant: 5R01DK127497-03

Determining the mechanism of IFIH1 disease-associated variants on beta-cell and immune responses in Type 1 diabetes

National Institutes of Health

Grant: 5F30DK105788-04

Type 1 IFN in Type 1 Diabetes: Influencing Beta-Cell and CD8+ T cell interactions

National Institutes of Health

Grant: 1UC4DK104207-01

Mice with autologous human T1D-derived immune systems and iPSC-derived beta cells

National Institutes of Health

Grant: 3T32DK108736-02S1

Interdisciplinary Graduate Program in Type 1 Diabetes and Biomedical Engineering

National Institutes of Health

Grant: 5R01DK103585-02

Immune Response to iPSC-Derived Beta Cells in Type 1 Diabetes

National Institutes of Health

Grant: 5P01AI042288-17

Administrative Core

National Institutes of Health

Grant: 5R21AI140044-02

Stress induced changes to the human beta cell proteome

greenLicense: https://www.biorxiv.org/about/FAQ#license

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/05/03/2021.05.03.441837.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.05.03.441837

repositoryhttps://doi.org/10.1101/2021.05.03.441837

https://doi.org/10.3389/fendo.2021.737276

Fields of Study

Pancreatic function and diabetesDiabetes and associated disordersCAR-T cell therapy research0301 basic medicine03 medical and health sciences

Keywords

Induced pluripotent stem cellBiologyCell biologyCell typeStem cellCellPTPN22T cellCD8Progenitor cellImmunologyGeneticsImmune systemGeneEmbryonic stem cellGenotypeSingle-nucleotide polymorphismautoimmunityInduced Pluripotent Stem CellsCell DifferentiationCD8-Positive T-LymphocytesRC648-665immunityDiseases of the endocrine glands. Clinical endocrinologyisogenicbeta cellsIslets of LangerhansEndocrinologyDiabetes Mellitus, Type 1Insulin-Secreting CellsHumanshumantype 1 diabetes mellitus

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being