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Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.05.17.444471Source: DataRank Database

Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

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Open Access

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Authors (15)

Harilaos Filippakis,Thomas R. Hougard,Heng Du ORCID,Chenyang Ye ORCID,Heng-Jia Liu ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W3159977684

National Institutes of Health

Grant: 3P30CA006516-41S6

CANCER CENTER SUPPORT GRANT

National Institutes of Health

Grant: 5K01DK116819-02

Impact of mitochondrial dynamics on the development of renal cysts in Tuberous Sclerosis Complex (TSC)

National Institutes of Health

Grant: 5R01HL146541-04

Pathogenic Mechanisms of Pulmonary Lymphangioleiomyomatosis

National Institutes of Health

Grant: 2P01CA120964-06A1

Molecular wiring and therapeutic targeting of the TSC-Rheb signaling network

greenLicense: other-oa

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/05/17/2021.05.17.444471.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.05.17.444471

repositoryhttps://doi.org/10.1101/2021.05.17.444471

https://doi.org/10.1073/pnas.2101268118

Fields of Study

Tuberous Sclerosis Complex ResearchVascular Tumors and AngiosarcomasRenal cell carcinoma treatment0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

mTORC1Downregulation and upregulationTSC2SerinePhosphoserineTSC1Cancer researchChemistryBiologyCell biologyPhosphorylationSignal transductionPI3K/AKT/mTOR pathwayBiochemistryGeneMice, Inbred C57BLMice, KnockoutMiceInterleukin-6Tuberous Sclerosis Complex 2 ProteinAnimalsMechanistic Target of Rapamycin Complex 1Transaminases

Sustainable Development Goals

SDG 3: 3. Good health