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Rampant transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of a human fungal pathogen

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.11.455996Source: DataRank Database

Rampant transposition following RNAi loss causes hypermutation and antifungal drug resistance in clinical isolates of a human fungal pathogen is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (25)IDs (PubMed, OpenAlex)SDGs (2)

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Open Access

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Authors (7)

Vikas Yadav ORCID,Cullen Roth ORCID,Tim A. Dahlmann ORCID,Ulrich Kück ORCID,Paul M. Magwene ORCID

Live enrichment

PubMed:30945415 OpenAlex:https://openalex.org/W4250896983

National Institutes of Health

Grant: 5R01AI050113-04

Functions of Cryptococcus neoformans mating type loci

National Institutes of Health

Grant: 5R37AI039115-23

Genetics of Cryptococcus sexual reproduction

National Institutes of Health

Grant: 5R01AI100272-08

Cryptococcus knockout and tag resource

National Institutes of Health

Grant: 5F31AI143136-02

Causes and Consequences of Hypermutability in Cryptococcus neoformans

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/08/11/2021.08.11.455996.full.pdf

GREENhttps://doi.org/10.1101/2021.08.11.455996

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/08/11/2021.08.11.455996.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.08.11.455996

https://doi.org/10.21203/rs.3.rs-804218/v1

Fields of Study

Fungal Infections and StudiesPlant Disease Resistance and GeneticsChromosomal and Genetic VariationsBiologyMedicine0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Somatic hypermutationBiologyCryptococcus neoformansGeneticsNonsense mutationGenomeAntifungal drugLocus (genetics)Drug resistanceTransposable elementCRISPRRNA interferenceMutationGeneMissense mutationCandida albicansRNA

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being