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Spatially Resolved In Silico Modeling of NKG2D Signaling Kinetics Reveals Key role of NKG2D and Vav1 Co-clustering in Generating Natural Killer cell Activation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.08.24.457567Source: DataRank Database

Spatially Resolved In Silico Modeling of NKG2D Signaling Kinetics Reveals Key role of NKG2D and Vav1 Co-clustering in Generating Natural Killer cell Activation is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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Authors (2)

Jayajit Das ORCID,Rajdeep Kaur Grewal ORCID

Live enrichment

PubMed:26207759 OpenAlex:https://openalex.org/W3194204927

National Institutes of Health

Grant: 3R01AI146581-03S1

Modeling Antibody-induced Immune Responses by NK cells in Mice and Humans (Resubmission 1)

National Institutes of Health

Grant: 5R01AI143740-03

Developing a predictive in silico toolkit for modeling NK cell responses against RNA virus infections

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/08/25/2021.08.24.457567.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.08.24.457567

repositoryhttps://doi.org/10.1101/2021.08.24.457567

https://doi.org/10.1371/journal.pcbi.1010114

Fields of Study

Immune Cell Function and InteractionT-cell and B-cell ImmunologyImmune cells in cancer0301 basic medicine03 medical and health sciences0302 clinical medicine

Keywords

In silicoNKG2DRobustness (evolution)Computational biologyCluster analysisRegulatorBiologyCell biologyComputer scienceArtificial intelligenceBiochemistryCytotoxicityIn vitroQH301-705.5LigandsLymphocyte ActivationKiller Cells, NaturalKineticsNK Cell Lectin-Like Receptor Subfamily KHumansComputer SimulationBiology (General)Proto-Oncogene Proteins c-vavResearch ArticleSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health