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BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.24.461749Source: DataRank Database

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (4 grants)OA: greenTopics (34)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (8)

Joshua Mathew ORCID,Gemma Moore ORCID,Sudipta Lahiri,Jennifer Garbarino ORCID,Joseph P. Eder ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3201768182

National Institutes of Health

Grant: 5R01CA215990-05

Elucidating Cancer Risk in BRCA2 and RAD51 Variants

National Institutes of Health

Grant: 3R35GM134947-02S1

Mechanisms of Human DNA Double-Strand Break Repair via Quantitative Single-Molecule Imaging - Equipment Supplement

National Institutes of Health

Grant: 1R01AI153040-01

Mechanism and Fidelity of RAG mediated DNA recombination

National Institutes of Health

Grant: 5P01CA247773-03

Polymerase theta, genome instability, and cancer

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/04/01/2021.09.24.461749.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.09.24.461749

repositoryhttps://doi.org/10.1101/2021.09.24.461749

https://www.biorxiv.org/content/biorxiv/early/2021/09/25/2021.09.24.461749.full.pdf

Fields of Study

DNA Repair MechanismsCRISPR and Genetic EngineeringBRCA gene mutations in cancer0301 basic medicine03 medical and health sciences

Keywords

RAD51Frameshift mutationBiologyMissense mutationGeneticsPALB2DNA mismatch repairNonsense mutationDNA repairBRCA2 ProteinCancer researchMutationGeneGermline mutationvariantsQH301-705.5ScienceQRMutation, MissenseDNA, Single-StrandedBRCA2homology-directed repairNucleoproteinshereditary cancerMedicineRad51 RecombinaseBiology (General)Cancer Biology

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being