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Two helices control the dynamic crosstalk between the catalytic domains of LRRK2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462278Source: DataRank Database

Two helices control the dynamic crosstalk between the catalytic domains of LRRK2 is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)OA: greenTopics (26)IDs (PubMed, OpenAlex)

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Authors (11)

Phillip C. Aoto ORCID,Robin Lorenz ORCID,Jian Wu ORCID,Sven H. Schmidt ORCID,Jascha T. Manschwetus ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W3204702236

National Institutes of Health

Grant: 1S10OD016234-01

Synapt G2-S System with HXMS Automation

National Institutes of Health

Grant: 5T32CA009523-10

BIOCHEMISTRY OF GROWTH REGULATION AND ONCOGENESIS

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/09/29/2021.09.29.462278.full.pdf

GREENhttps://doi.org/10.1101/2021.09.29.462278

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/09/29/2021.09.29.462278.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.09.29.462278

https://dx.doi.org/10.1101/2021.09.29.462278

Fields of Study

Plant biochemistry and biosynthesisMicrobial Natural Products and BiosynthesisProtein Structure and DynamicsBiologyChemistry0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

LRRK2Allosteric regulationHelix (gastropod)Protein kinase domainKinaseCrosstalkChemistryLeucine-rich repeatBiophysicsTransferaseHydrogen–deuterium exchangeCrystallographyBiochemistryBiologyPhysicsEnzymeMutationHydrogen