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Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462463Source: DataRank Database

Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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Enrichment:Funding (4 grants)OA: hybridTopics (31)IDs (PubMed)

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Authors (3)

Jeffrey van Haren ORCID,Torsten Wittmann ORCID,Alessandro Dema ORCID

Live enrichment

PubMed:35090591

National Institutes of Health

Grant: 5R01NS107480-03

Probing Microtubule Function in Neuronal Development

National Institutes of Health

Grant: 1S10OD028611-01

Wide-field super-resolution spinning disk confocal microscope

National Institutes of Health

Grant: 5R21CA224194-02

Dissecting protein activities by reversible photo-inactivation

National Institutes of Health

Grant: 1S10RR026758-01

Spinning disk confocal / FRAP microscope for quantitative live cell imaging

hybridLicense: CC BY NC ND

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.09.29.462463

https://doi.org/10.1101/2021.09.29.462463

https://www.biorxiv.org/content/biorxiv/early/2021/10/01/2021.09.29.462463.full.pdf

https://doi.org/10.1016/j.cub.2022.01.017

http://www.cell.com/article/S0960982222000288/pdf

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

570Biomedical and clinical sciences1.1 Normal biological development and functioning612Spindle ApparatusmetaphaseMedical and Health SciencesMicrotubulesspindle positionUnderpinning researchGeneticsPsychologyAnimalsoptogeneticsLOV2mitosisMammalsKIF18BPsychology and Cognitive SciencesBiological Sciencesmicrotubule dynamicsEB1spindle sizeBiochemistry and Cell BiologyGeneric health relevanceastral microtubulesMicrotubule-Associated ProteinsDevelopmental Biology