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Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.22.465389Source: DataRank Database

Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2 is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (44)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (9)

Xianchi Dong,Adam DeCosta ORCID,Yang Su ORCID,Fiona Angrisano ORCID,Katarzyna Sala ORCID

Live enrichment

PubMed:19022398 OpenAlex:https://openalex.org/W3209786024

National Institutes of Health

Grant: 6R01AI095686-02

Structural Vaccinology of the Malaria Sporozoite Surface Sheath

Wellcome Trust

Grant: unidentified

unidentified

UK Research and Innovation

Grant: MR/N00227X/1

Dissecting the molecular basis for gamete recognition in the malaria parasite, and its targeting to block transmission

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/10/24/2021.10.22.465389.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.10.22.465389

repositoryhttps://doi.org/10.1101/2021.10.22.465389

repositoryhttps://www.repository.cam.ac.uk/handle/1810/333544

Fields of Study

Malaria Research and ControlInvertebrate Immune Response MechanismsInsect Resistance and Genetics0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

EctodomainBiologyMonoclonal antibodyPlasmodium bergheiVirologyAntibodyGametePlasmodium (life cycle)Cell biologyMalariaGeneticsParasite hostingReceptorImmunology570QH301-705.5Scienceinfectious diseasemembrane fusionProtozoan ProteinsBiophysical Phenomenamalaria transmission-blocking vaccineHAP2molecular biophysicsstructural biologyAnimalsBiology (General)Microbiology and Infectious DiseaseQmicrobiologyRAntibodies, MonoclonalCulicidaeGerm CellsMedicinegamete fusogenBinding Sites, AntibodyProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being