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Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.19.469258Source: DataRank Database

Patient induced pluripotent stem cell-derived hepatostellate organoids establish a basis for liver pathologies in telomeropathies is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (36)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (14)

Melissa S. Kim ORCID,Joshua H. Rhoades ORCID,N. M. Johnson ORCID,Corbett T. Berry ORCID,Sarah Root ORCID

Live enrichment

PubMed:30945415 OpenAlex:https://openalex.org/W3215549827

National Institutes of Health

Grant: 1R01HL148821-01

IDENTIFICATION AND PRECLINICAL EVALUATION OF NOVEL THERAPEUTIC APPROACHES TO DYSKERATOSIS CONGENITA

National Institutes of Health

Grant: 5P30DK050306-08

Center for Digestive and Liver Diseases

National Institutes of Health

Grant: 5R21AG054209-02

A novel and tractable model to address telomere dysfunction in a human tissue

greenLicense: CC BY NC ND

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/11/19/2021.11.19.469258.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.11.19.469258

repositoryhttps://doi.org/10.1101/2021.11.19.469258

https://doi.org/10.1016/j.jcmgh.2023.06.003

Fields of Study

Telomeres, Telomerase, and SenescenceRenal and related cancersPluripotent Stem Cells Research0301 basic medicine03 medical and health sciences

Keywords

BiologyInduced pluripotent stem cellHepatic stellate cellStem cellTelomeraseTelomerePhenotypeCancer researchCell biologyPathologyImmunologyGeneticsMedicineEmbryonic stem cellEndocrinologyOrganoidHyperplasiaStellate CellInduced Pluripotent Stem CellsNuclear ProteinsCell DifferentiationCell Cycle ProteinsRC799-869Diseases of the digestive system. GastroenterologyDKC1Dyskeratosis CongenitaOrganoidsLiverHumansHepatocyteOriginal Research

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being