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Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.08.471792Source: DataRank Database

Cylindromatosis Drives Synapse Pruning and Weakening by Promoting Macroautophagy through Akt-mTOR Signaling is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2021). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Open Access1 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)OA: greenTopics (33)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Hongyu Ruan ORCID,Huihui Dai,Mary Catherine Skolfield ORCID,Hannah Phillips ORCID,Wendi J. Burnette

Live enrichment

PubMed:19022398 OpenAlex:https://openalex.org/W4200622199

National Institutes of Health

Grant: 5R01NS026761-02

GROWTH FACTORS IN INTRASTRIATAL TRANSPLANTS

National Institutes of Health

Grant: 5P51RR000168-26

NEW ENGLAND REGIONAL PRIMATE RESEARCH CENTER

National Institutes of Health

Grant: 5R01NS093097-05

Prefrontal AMPA receptors in FTD Pathogenesis

National Institutes of Health

Grant: 1R01MH106489-01

Nonproteolytic Polyubiquitin Chains at the Synapse

National Institutes of Health

Grant: 1R56NS122351-01

CYLD in Synapse Pruning and Pathogenesis of FTD

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2021/12/10/2021.12.08.471792.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2021.12.08.471792

repositoryhttps://doi.org/10.1101/2021.12.08.471792

https://doi.org/10.1038/s41380-022-01571-1

Fields of Study

Ubiquitin and proteasome pathwaysCorneal Surgery and TreatmentsAutophagy in Disease and Therapy0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

PI3K/AKT/mTOR pathwayAutophagyRHEBSynaptogenesisProtein kinase BSynapseCell biologySynaptic plasticityBiologyNeuroscienceDeubiquitinating enzymePostsynaptic potentialDendritic spineUbiquitinHippocampal formationSignal transductionmTORC1GeneticsReceptorMammalsMiceDeubiquitinating EnzymesTOR Serine-Threonine KinasesMacroautophagySynapsesAnimalsProto-Oncogene Proteins c-akt

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being