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On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.19.476918Source: DataRank Database

On the illusion of auxotrophy: met15Δ yeast cells can grow on inorganic sulfur thanks to the previously uncharacterized homocysteine synthase Yll058w is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Enrichment:Funding (6 grants)OA: greenTopics (30)IDs (PubMed, OpenAlex)

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Authors (17)

Saurin Bipin Parikh ORCID,Nelson Castilho Coelho ORCID,Aaron Wacholder ORCID,Ivan A. Belashov ORCID,Sara Zdancewicz ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4205287946

National Institutes of Health

Grant: 1P01CA250984-01A1

Identifying Metabolic Vulnerabilities in Lung Cancer

National Institutes of Health

Grant: 5R00GM108865-05

Deciphering the mechanisms and dynamics of proto-gene evolution

National Science Foundation

Grant: 2144349

CAREER: Investigation Of How Proto-Gene Expression Impacts Growth In Budding Yeast

National Institutes of Health

Grant: 5F32GM129929-03

Investigating mechanisms of de novo gene birth in Saccharomyces cerevisiae

National Institutes of Health

Grant: 3P30CA076292-24S2

Moffitt Cancer Center Support Grant

National Institutes of Health

Grant: 1S10OD023402-01A1

Bringing Untargeted Metabolomics to Pitt

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/11/08/2022.01.19.476918.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.01.19.476918

repositoryhttps://doi.org/10.1101/2022.01.19.476918

https://doi.org/10.1016/j.jbc.2022.102697

Fields of Study

Fungal and yeast genetics researchBiofuel production and bioconversionFermentation and Sensory Analysis0301 basic medicine03 medical and health sciences

Keywords

Sulfur metabolismComplementationAuxotrophyBiologyBiochemistryCystathionine beta synthaseYeastSulfurSaccharomyces cerevisiaeHydrogen sulfideHomocysteineMethionineMethionine synthaseGeneticsATP synthaseGeneChemistryAmino acidPhenotypeCysteine SynthaseSaccharomyces cerevisiae ProteinsMutationCarbon-Oxygen LyasesHumansResearch Article