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Histone deacetylase inhibitor induces acetyl-CoA depletion leading to lethal metabolic stress in RAS-pathway activated cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.31.478570Source: DataRank Database

Histone deacetylase inhibitor induces acetyl-CoA depletion leading to lethal metabolic stress in RAS-pathway activated cells is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)OA: greenTopics (24)IDs (PubMed, OpenAlex)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Pierre-Christian Violet ORCID,Maryam Safari ORCID,Carole Sourbier ORCID,W. Marston Linehan ORCID,Robert W. Robey ORCID

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W4210800845

National Institutes of Health

Grant: 1ZIADK053212-18

Ascorbic acid as a pharmacologic agent in disease treatment

European Commission

Grant: 841313

Machine learning prediction for breast cancer therapy

French National Research Agency (ANR)

Grant: ANR-11-INBS-0013

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/02/01/2022.01.31.478570.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.01.31.478570

repositoryhttps://doi.org/10.1101/2022.01.31.478570

https://doi.org/10.3390/cancers14112643

Fields of Study

Histone Deacetylase Inhibitors ResearchAutophagy in Disease and TherapyProtein Degradation and Inhibitors0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

RomidepsinHistone deacetylaseHistone deacetylase inhibitorCancer researchKRASAcetylationPhenotypeBiologyHistoneChemistryCell biologyBiochemistryMutationGeneHDAC inhibitorsacetyl-CoA metabolismArticleRAS

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being