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Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.08.487470Source: DataRank Database

Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (37)IDs (PubMed, OpenAlex)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Colleen Noviello ORCID,Ryan Hibbs ORCID,Rebecca J. Howard ORCID,Erik Lindahl ORCID,Yuxuan Zhuang ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4224275341

Swedish Research Council

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5R01NS120496-06

Structural basis of nicotinic acetylcholine receptor gating and toxin inhibition

European Commission

Grant: 823830

BioExcel Centre of Excellence for ComputationalBiomolecular Research

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/04/08/2022.04.08.487470.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.04.08.487470

repositoryhttps://doi.org/10.1101/2022.04.08.487470

https://doi.org/10.1073/pnas.2208081119

Fields of Study

Nicotinic Acetylcholine Receptors StudyReceptor Mechanisms and SignalingIon channel regulation and function0301 basic medicine03 medical and health sciences

Keywords

ChemistryBiophysicsAllosteric regulationTransmembrane domainLipid bilayerIon channelLigand-gated ion channelNicotinic agonistLigand (biochemistry)Transmembrane proteinNicotinic acetylcholine receptorMembrane potentialReceptorMembraneBiochemistryBiologyAWH enhanced samplingalpha7 Nicotinic Acetylcholine Receptormolecular dynamic simulationPhenylurea CompoundsIsoxazolesalpha-7 nicotinic receptorBiological SciencesLigand-Gated Ion ChannelsReceptors, NicotinicLigandsLipidscoarse-grained simulationCholesterolpentameric ligand gated ion channelHumansnicotinic receptor

Sustainable Development Goals

SDG 0: Affordable and clean energy