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Glucagon-Like Peptide-1 Receptor Activation Stimulates PKA-Mediated Phosphorylation of Raptor and this Contributes to the Weight Loss Effect of Liraglutide

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.21.489078Source: DataRank Database

Glucagon-Like Peptide-1 Receptor Activation Stimulates PKA-Mediated Phosphorylation of Raptor and this Contributes to the Weight Loss Effect of Liraglutide is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Enrichment:Funding (4 grants)OA: greenTopics (41)IDs (PubMed, OpenAlex)

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Authors (8)

Dianxin Liu ORCID,Gai-Linn K. Besing ORCID,Ritika Raghavan ORCID,Blair J. Ellis,Ryan P. Ceddia ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4280641335

National Institutes of Health

Grant: 1S10OD028455-01

Promethion Core System

National Institutes of Health

Grant: 5R01DK116625-03

Dissecting PKA activation of mTORC1 and its function in adipose tissue

National Institutes of Health

Grant: 1R01DK132852-01A1

Molecular mechanisms mediating metabolic benefits of glucagon-like peptide-1 receptor agonists

National Institutes of Health

Grant: 4R01DK097361-04

Regulation of Food Intake via the Glucagon-Like Peptide-1 Receptor

greenLicense: CC BY

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/01/03/2022.04.21.489078.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.04.21.489078

repositoryhttps://doi.org/10.1101/2022.04.21.489078

https://doi.org/10.7554/elife.80944

Fields of Study

Diabetes Treatment and ManagementMetabolism, Diabetes, and CancerPancreatic function and diabetes0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

LiraglutideRibosomal protein s6PhosphorylationBiologyReceptorProtein kinase AEndocrinologyInternal medicineChemistryBiochemistryProtein phosphorylationType 2 diabetesMedicineDiabetes mellitusQH301-705.5ScienceCHO CellsMechanistic Target of Rapamycin Complex 1Glucagon-Like Peptide-1 Receptorbody weightMiceCricetulusCricetinaeWeight LossAnimalsObesityBiology (General)QRCell BiologyRegulatory-Associated Protein of mTORCyclic AMP-Dependent Protein Kinasesglucagon-like peptide-1raptormechanistic target of rapamycin