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Characterization of human immunodeficiency virus (HIV-1) envelope glycoprotein variants selected for resistance to a CD4-mimetic compound

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.21.489129Source: DataRank Database

Characterization of human immunodeficiency virus (HIV-1) envelope glycoprotein variants selected for resistance to a CD4-mimetic compound is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)OA: greenTopics (38)IDs (PubMed, OpenAlex)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Jonathan Richard ORCID,Catherine Bourassa ORCID,Guillaume Goyette ORCID,Ta-Jung Chiu ORCID,Hung-Ching Chen ORCID

Live enrichment

PubMed:19965766 OpenAlex:https://openalex.org/W4280574581

National Institutes of Health

Grant: 5UM1AI164562-03

Enterprise for Research and Advocacy to Stop and Eradicate HIV (ERASE-HIV)

National Institutes of Health

Grant: 1R01AI150322-01

Characterizing HIV-1 Env conformations susceptible to attack by non-neutralizing antibodies

National Institutes of Health

Grant: 5R01AI148379-02

Assessing ADCC and Fc-mediated Protection against HIV

Canadian Institutes of Health Research

Grant: unidentified

unidentified

National Institutes of Health

Grant: 5P01AI150471-26

Structure-Based Antagonism of HIV-1 Envelope Function in Cell Entry

National Institutes of Health

Grant: 5R01AI124982-08

Conformational Landscape of the HIV-1 Envelope Glycoproteins

National Institutes of Health

Grant: 5R33AI129017-05

Reducing viral reservoirs by opening HIV-1 Env to antibody attack

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/04/23/2022.04.21.489129.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.04.21.489129

repositoryhttps://doi.org/10.1101/2022.04.21.489129

https://doi.org/10.1128/jvi.00636-22

Fields of Study

HIV Research and TreatmentHIV/AIDS drug development and treatmentHepatitis C virus research0301 basic medicine03 medical and health sciences

Keywords

Gp41GlycoproteinConformational changeVirusViral envelopeVirologyBiologyViral entryTrimerViral replicationHuman immunodeficiency virus (HIV)Molecular biologyChemistryAntibodyBiochemistryGeneticsEpitopeBinding SitesProtein Conformationenv Gene Products, Human Immunodeficiency VirusHIV InfectionsHIV Envelope Protein gp120GuanidinesHIV Envelope Protein gp41Receptors, HIVIndenesHIV Fusion InhibitorsCD4 AntigensDrug Resistance, ViralMutationHIV-1HumansGlycoproteins

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being