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Senescent Preosteoclast Secretome Promotes Metabolic Syndrome-Associated Osteoarthritis through Cyclooxygenase 2

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.05.490792Source: DataRank Database

Senescent Preosteoclast Secretome Promotes Metabolic Syndrome-Associated Osteoarthritis through Cyclooxygenase 2 is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0. It has been cited 5 times.

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Scored on demand from live citation data

Open Access5 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (4 grants)OA: greenTopics (42)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Guanqiao Liu ORCID,Bahram Mohajer ORCID,Jiekang Wang ORCID,Alena Shen ORCID,Weixin Zhang ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4229016860

National Institutes of Health

Grant: 5R01AG072090-05

Identifying A Skeleton-Derived Factor for Vascular Aging

National Institutes of Health

Grant: 5R01AR079620-02

Effect of statin intake on Non-traumatic Generalized Knee Osteoarthritis

National Institutes of Health

Grant: 1P01AG066603-01A1

Skeleton and Joint Degeneration with Aging

National Institutes of Health

Grant: 1R01AG068226-01

Role of Cellular Senescence in the Bone-Brain Interplay

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/05/05/2022.05.05.490792.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.05.05.490792

repositoryhttps://doi.org/10.1101/2022.05.05.490792

https://doi.org/10.7554/elife.79773

Fields of Study

Osteoarthritis Treatment and MechanismsBone Metabolism and DiseasesNF-κB Signaling Pathways0301 basic medicine03 medical and health sciences

Keywords

OsteoarthritisOsteoblastMedicineCartilagePhenotypeSubchondral boneSenescenceInternal medicineOsteoclastBone remodelingEndocrinologyCancer researchPathologyArticular cartilageBiologyIn vitroAnatomyGeneReceptorGeneticsMetabolic SyndromeCyclooxygenase 2 InhibitorsQH301-705.5ScienceQRDinoprostoneUnited StatesMicesubchondral thickeningCyclooxygenase 2senescence-associated secretory phenotypecellular senescenceAnimalsHumansBiology (General)Secretome

Sustainable Development Goals

SDG 3: 3. Good health