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Deletion mapping of regulatory elements for GATA3 reveals a distal T helper 2 cell enhancer involved in allergic diseases

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.24.493112Source: DataRank Database

Deletion mapping of regulatory elements for GATA3 reveals a distal T helper 2 cell enhancer involved in allergic diseases is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (26)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (10)

Patrick C. Fiaux ORCID,Arko Sen ORCID,Ishika Luthra ORCID,Aaron J. Ho,Aaron R. Chen ORCID

Live enrichment

PubMed:21097893 OpenAlex:https://openalex.org/W4281551785

National Institutes of Health

Grant: 3R01DK122607-01S1

Genetic mechanisms of type 1 diabetes risk in stress-induced pancreatic islets

National Institutes of Health

Grant: 5R35HG011315-03

Using genomic perturbations to understand trait-associated human genetic variation

National Institutes of Health

Grant: 5R01AI107027-07

Treg development and function controlled by cis-regulatory circuits

greenLicense: cc-by

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/05/25/2022.05.24.493112.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.05.24.493112

repositoryhttps://doi.org/10.1101/2022.05.24.493112

Fields of Study

Single-cell and spatial transcriptomicsEpigenetics and DNA MethylationGenomics and Chromatin Dynamics0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

EnhancerGenome-wide association studyBiologyExpression quantitative trait lociGATA3GeneticsCandidate geneQuantitative trait locusJurkat cellsGeneComputational biologyGenetic associationRegulatory sequenceLocus (genetics)Regulation of gene expressionTranscription factorT cellImmune systemSingle-nucleotide polymorphismGenotype

Sustainable Development Goals

SDG 0: Good health and well-being