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A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.31.494266Source: DataRank Database

A nuclear export signal in KHNYN required for its antiviral activity evolved as ZAP emerged in tetrapods is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (35)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (11)

Mattia Ficarelli ORCID,Harry Wilson ORCID,Dorota Kmieć ORCID,Rebecca L Youle ORCID,Joseph J. Wanford ORCID

Live enrichment

PubMed:19767382 OpenAlex:https://openalex.org/W4282044092

Wellcome Trust

Grant: 206200/Z/17/Z

UK Research and Innovation

Grant: MR/R50225X/1

Kings College London and DRI NPIF Studentships 2017

Deutsche Forschungsgemeinschaft

Grant: unidentified

unidentified

Wellcome Trust

Grant: 206200

Type III interferons in immunity against bacteria

UK Research and Innovation

Grant: MR/W018519/1

The mechanistic basis for the ZAP antiviral system targeting viral and cellular RNAs

UK Research and Innovation

Grant: MR/S000844/1

Regulation of HIV-1 and Ebola virus replication by CpG dinucleotides, ZAP and TRIM25

greenLicense: cc-by-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/06/01/2022.05.31.494266.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.05.31.494266

repositoryhttps://doi.org/10.1101/2022.05.31.494266

repositoryhttps://figshare.com/articles/journal_contribution/A_nuclear_export_signal_in_KHNYN_required_for_its_antiviral_activity_evolved_as_ZAP_emerged_in_tetrapods/21995669

Fields of Study

interferon and immune responsesImmune Response and InflammationHIV Research and Treatment0301 basic medicine03 medical and health sciences

Keywords

BiologyCullinNuclear localization sequenceCell biologyUbiquitinNuclear export signalNEDD8Nuclear transportCytoplasmZinc fingerGeneticsUbiquitin ligaseGeneCell nucleusTranscription factorNuclear Export SignalsModel organisms570Ubiquitin-Protein LigasesRNA-Binding ProteinsInfectious DiseaseCullin ProteinsVirus ReplicationVirus-Cell InteractionsEvolution, Molecular616AnimalsRNA, ViralInterferonsStructural Biology & Biophysics

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Life below water