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Transcriptome-Wide Gene-Gene Interaction Association Study Elucidates Pathways and Functional Enrichment of Complex Traits

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.16.504187Source: DataRank Database

Transcriptome-Wide Gene-Gene Interaction Association Study Elucidates Pathways and Functional Enrichment of Complex Traits is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0.

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TWIS meta-analyzed summary statistics · Dryad

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Enrichment:Funding (11 grants)OA: greenTopics (28)Linked Datasets (1)DataCite Reuse (1)IDs (PubMed, OpenAlex)

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Authors (8)

Christopher H. Arehart ORCID,Andrew D. Grotzinger ORCID,Travis Mize ORCID,Maizy S. Brasher ORCID,Jerry A. Stitzel ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4292121908

National Institutes of Health

Grant: 5R01DA044283-04

Deep Sequencing, Phenotyping, and Imputation in Large-Scale Biobanks: A Novel and Cost-Effective Framework to Identify Rare Mutations Associated with Addiction

National Institutes of Health

Grant: 1U01DA051937-01

Identification of genes and genetic networks contributing to opioid use disorder traits in the Hybrid Rat Diversity Panel

National Institutes of Health

Grant: 3RF1AG064465-01S2

Sleep Disruption and Alzheimer's Disease Pathology

National Institutes of Health

Grant: 1R01AG046938-01A1

Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife)

National Institutes of Health

Grant: 2T32DA017637-11

Research Training - Genetics of Substance Abuse

National Institutes of Health

Grant: 5R01HL128782-03

Genomics of blood pressure-induced target organ damage

National Institutes of Health

Grant: 1R03AA026733-01

Examining the role of a GCKR polymorphism in alcohol-related behaviors in mice

National Science Foundation

Grant: 1532235

MRI Collaborative Consortium: Acquisition of a Shared Supercomputer by the Rocky Mountain Advanced Computing Consortium

National Science Foundation

Grant: 1532236

MRI Collaborative Consortium: Acquisition of a Shared Supercomputer by the Rocky Mountain Advanced Computing Consortium

National Institutes of Health

Grant: 5R01MH100141-10

Estimating the genetic and environmental architecture of psychiatric disorders

Wellcome Trust

Grant: unidentified

unidentified

greenLicense: cc-by-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/08/17/2022.08.16.504187.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.08.16.504187

repositoryhttps://doi.org/10.1101/2022.08.16.504187

https://doi.org/10.1371/journal.pgen.1010693

Fields of Study

Bioinformatics and Genomic NetworksGenetic Associations and EpidemiologyRNA Research and Splicing0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

EpistasisInterpretabilityGeneBiologyTranscriptomeComputational biologyGeneticsGene interactionGene regulatory networkLocus (genetics)ReplicateGene expressionComputer scienceMachine learningMultifactorial InheritancePhenotypeEpistasis, GeneticGene Regulatory NetworksQH426-470Polymorphism, Single NucleotideResearch ArticleGenome-Wide Association Study

TWIS meta-analyzed summary statistics

10.5061/dryad.866t1g1twDryad