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Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy

medRxiv(2022)10.1101/2022.08.23.22278845Source: DataRank Database

Loss of symmetric cell division of apical neural progenitors drives DENND5A -related developmental and epileptic encephalopathy is a research paper published in medRxiv (2022). On theSindex it has a DataRank of 0.

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Enrichment:Funding (6 grants)OA: greenTopics (55)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (85)

Vincent Francis ORCID,Sheng‐Jia Lin ORCID,Fares Kharfallah ORCID,Vladimir S. Fonov ORCID,Maxime Levesque

Live enrichment

PubMed:38352438 OpenAlex:https://openalex.org/W4293150221

National Institutes of Health

Grant: 1U01HG011758-01

Baylor College of Medicine - Mendelian Genomics Research Center (BCM-MGRC)

National Institutes of Health

Grant: 5U01HG007672-04

An integrated and diverse genomic medicine program for undiagnosed diseases

National Institutes of Health

Grant: 1U01HG007943-01

Clinical Genome Wide Sequencing Core for the Undiagnosed Disease Network

National Institutes of Health

Grant: 3UM1HG006542-05S1

Baylor Johns Hopkins Center for Mendelian Genetics

National Institutes of Health

Grant: 3R35NS105078-02S1

STRUCTURAL VARIATION IN NEUROLOGICAL DISEASE

Canadian Institutes of Health Research

Grant: unidentified

unidentified

greenLicense: cc-by-nd

repositoryhttps://www.medrxiv.org/content/medrxiv/early/2022/08/26/2022.08.23.22278845.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.08.23.22278845

repositoryhttps://doi.org/10.1101/2022.08.23.22278845

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38352438

Fields of Study

Microtubule and mitosis dynamicsGenetics and Neurodevelopmental DisordersEpigenetics and DNA Methylation0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

NeurogenesisBiologyProgenitor cellMitosisNeural stem cellNeuroscienceSubventricular zoneCell divisionCentrosomeAsymmetric cell divisionCell biologyStem cellCellCell cycleGeneticsMaleMedical SciencesBioinformaticsScienceInduced Pluripotent Stem Cells610Neural Stem Cells: cytologyMembrane Proteins: metabolismArticleBiomedical InformaticsMiceNeural Stem Cells616Medical SpecialtiesMedicine and Health SciencesAnimalsHumansGuanine Nucleotide Exchange FactorsInduced Pluripotent Stem Cells: cytologyAnimalNeural Stem Cells: metabolismQMembrane Proteins: geneticsCell PolarityMembrane ProteinsGuanine Nucleotide Exchange Factors: geneticsDisease Models, AnimalGuanine Nucleotide Exchange Factors: metabolismOncologyDisease ModelsNeurogenesis: geneticsFemaleInduced Pluripotent Stem Cells: metabolisminfo:eu-repo/classification/ddc/500

Sustainable Development Goals

SDG 10: 10. No inequality