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Cholinergic Modulation Shifts the Response of CA1 Pyramidal Cells to Depolarizing Ramps via TRPM4 Channels with Potential Implications for Place Field Firing

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.24.513511Source: DataRank Database

Cholinergic Modulation Shifts the Response of CA1 Pyramidal Cells to Depolarizing Ramps via TRPM4 Channels with Potential Implications for Place Field Firing is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0.

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Enrichment:Funding (2 grants)OA: greenTopics (38)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (4)

Carol Upchurch ORCID,Carmen C. Canavier ORCID,Sonia Gasparini ORCID,Crescent L. Combe ORCID

Live enrichment

PubMed:37404129 OpenAlex:https://openalex.org/W4307607660

National Institutes of Health

Grant: 1R01MH115832-01

CRCNS: Cholinergic contribution to hippocampal information processing

National Science Foundation

Grant: 2018936

CC* Compute: Compute Cluster for Computational Sciences at Louisiana State University Health Sciences Center – New Orleans (LSUHSC-NO)

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/11/17/2022.10.24.513511.full.pdf

GREENhttps://doi.org/10.7554/elife.84387

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/11/17/2022.10.24.513511.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.10.24.513511

repositoryhttps://doi.org/10.1101/2022.10.24.513511

Fields of Study

Ion Channels and ReceptorsNicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology ResearchBiologyMedicine0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

ChemistryCarbacholBiophysicsCholinergicTransient receptor potential channelNeuroscienceDepolarizationAgonistReceptorBiologyBiochemistrynanodomainhippocampusQH301-705.5multicompartmental modelingSciencePyramidal CellsQRCholinergic AgentsTRPM Cation ChannelsCholinergic Agonistspatch clampReceptors, MuscarinicRatsnonspecific cation currentneuromodulationMedicineAnimalsBiology (General)

Sustainable Development Goals

SDG 0: Good health and well-being