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BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.28.522061Source: DataRank Database

BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2022). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)OA: greenTopics (43)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (5)

Christopher Dombrowski,Jody L. Plank ORCID,Ryan B. Jensen ORCID,Stephen C. Kowalczykowski ORCID,Jason C. Bell ORCID

Live enrichment

PubMed:19162232 OpenAlex:https://openalex.org/W4313365796

National Institutes of Health

Grant: 5R35GM131900-03

Single-molecule visualization and mechanisms of DNA recombination and intersecting DNA transactions

National Institutes of Health

Grant: 5T32GM007377-22

TRAINING IN MOLECULAR AND CELLULAR BIOLOGY

National Institutes of Health

Grant: 1R01GM064745-01

Single-Molecule Assembly of Protein-DNA Complexes

National Institutes of Health

Grant: 5F32CA136103-02

Mismatch Repair and the Fidelity Enforcement of Homologous Recombination

National Institutes of Health

Grant: 5R37GM062653-22

MECHANISTIC STUDIES OF GENETIC RECOMBINATION

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2022/12/29/2022.12.28.522061.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2022.12.28.522061

repositoryhttps://doi.org/10.1101/2022.12.28.522061

https://doi.org/10.1073/pnas.2221971120

Fields of Study

DNA Repair MechanismsCRISPR and Genetic EngineeringBRCA gene mutations in cancer0301 basic medicine03 medical and health sciences

Keywords

RAD51Homologous recombinationProtein filamentReplication protein ADNABRCA2 ProteinDNA repairDNA damageCell biologyBiologyChemistryBiophysicsMolecular biologyGeneticsDNA-binding proteinMutationGene570DNA recombinationOncology and CarcinogenesisGenes, BRCA2DNA, Single-Strandedsingle-molecule visualizationRare Diseasesbreast cancerSingle-Stranded2.1 Biological and endogenous factorsHumansCancerBiomedical and Clinical Sciences500Biological SciencesBRCA2GenesWomen's HealthRad51 RecombinaseBiotechnologyProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being