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The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.27.525934Source: DataRank Database

The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 1 time.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (1 grants)OA: greenTopics (30)IDs (PubMed, OpenAlex)SDGs (1)

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Open Access

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Reusable (0/3)

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Authors (4)

David M. Hercules ORCID,Eric A. Ortlund ORCID,C. Denise Okafor ORCID,Suzanne G. Mays ORCID

Live enrichment

PubMed:36747705 OpenAlex:https://openalex.org/W4318397871

National Institutes of Health

Grant: 1R21DK114213-01

A pilot study to target out-of-dialysis-unit versus dialysis-unit blood pressure

greenLicense: CC BY NC ND

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/01/28/2023.01.27.525934.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.01.27.525934

repositoryhttp://dx.doi.org/10.1101/2023.01.27.525934

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36747705

Fields of Study

Estrogen and related hormone effectsDrug Transport and Resistance MechanismsComputational Drug Discovery Methods0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Allosteric regulationNuclear receptorTranscription factorLigand (biochemistry)ReceptorSignal transductionFunction (biology)Cell biologyAllosteric modulatorChemistryBiologyBiochemistryGeneStructure-functionReceptors, Cytoplasmic and NuclearMolecular dynamicsMolecular Dynamics SimulationLigandsLigand regulationLRH-1Research ArticlesAllosteric SiteTranscription FactorsProtein Binding

Sustainable Development Goals

SDG 0: Reduced inequalities