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A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.31.524747Source: DataRank Database

A new microphysiological system shows hypoxia primes human ISCs for interleukin-dependent rescue of stem cell activity is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (13 grants)OA: greenTopics (23)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (15)

R. Jarrett Bliton ORCID,Joseph Burclaff ORCID,Michael Czerwinski ORCID,Jintong Liu ORCID,Jessica M. Trueblood

Live enrichment

PubMed:36778265 OpenAlex:https://openalex.org/W4318769806

National Institutes of Health

Grant: 7R01DK109559-06

DEVELOPMENT OF HUMAN INTESTINAL SIMULACRA

National Institutes of Health

Grant: 1F32DK124929-01A1

Determining the effects of Sox9 on the cell cycle of intestinal stem cells

National Institutes of Health

Grant: 5K04DK002019-02

MECHANISMS IN THE REGULATION OF PROLACTIN SECRETION

National Science Foundation

Grant: 1846911

CAREER: Reconfigurable Microfluidic-Microbalance Sensors to Monitor and Optimize the Performance of Microphysiological Models

National Science Foundation

Grant: 1160483

NSF Nanosystems Engineering Research Center for Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST)

National Institutes of Health

Grant: 7F31DK118859-02

Magnitude and Duration of Hypoxia Direct Intestinal Stem Cell Function

National Institutes of Health

Grant: 5P30DK034987-28

Administrative Core and Enrichment Program

National Science Foundation

Grant: 2033997

Bio-MAPS: BioMolecular-Array Patterns for Precision Differentiation of Intestinal Stem Cells

NIDDK NIH HHS

Grant: P30 DK034987

NIDDK NIH HHS

Grant: F32 DK124929

NIDDK NIH HHS

Grant: R01 DK109559

NIDDK NIH HHS

Grant: F31 DK118859

NICHD NIH HHS

Grant: R01 HD095876

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/02/01/2023.01.31.524747.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.01.31.524747

repositoryhttp://dx.doi.org/10.1101/2023.01.31.524747

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36778265

Fields of Study

Cancer Cells and MetastasisMesenchymal stem cell research3D Printing in Biomedical Research0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Hypoxia (environmental)Stem cellHypoxia-inducible factorsCellBiologyStem cell factorInflammationInterleukinCancer researchCell biologyImmunologyCytokineChemistryOxygenBiochemistryProgenitor cellArticle

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being