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Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.01.526549Source: DataRank Database

Multi-input drug-controlled switches of mammalian gene expression based on engineered nuclear hormone receptors is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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Authors (4)

Nicholas T. Perry ORCID,Sunny Zhang ORCID,Tanja Kortemme ORCID,Simon Kretschmer ORCID

Live enrichment

PubMed:36778233 OpenAlex:https://openalex.org/W4319040599

National Institutes of Health

Grant: 5R01GM110089-02

Computational design of protein-based small-molecule biosensors

National Institutes of Health

Grant: 3R35GM145236-03S1

Equipment Supplement - Computational design of proteins and protein functions

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/02/01/2023.02.01.526549.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.01.526549

repositoryhttp://dx.doi.org/10.1101/2023.02.01.526549

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36778233

Fields of Study

CAR-T cell therapy researchViral Infectious Diseases and Gene Expression in InsectsVirus-based gene therapy research0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Nuclear receptorControllabilityAgonistComputational biologyRetinoid X receptorReceptorCorepressorDrug discoveryTranscription factorCell biologyComputer scienceBiologyChemistryGeneBioinformaticsBiochemistryMathematicsBinding SitesGenes, ReporterReceptors, Cytoplasmic and NuclearDrug and Narcotic ControlGene ExpressionHumansLigandsArticle

Sustainable Development Goals

SDG 0: Good health and well-being