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Aryl hydrocarbon receptor knockout accelerates PanIN formation and fibro-inflammation in a mutant Kras -driven pancreatic cancer model

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.01.526625Source: DataRank Database

Aryl hydrocarbon receptor knockout accelerates PanIN formation and fibro-inflammation in a mutant Kras -driven pancreatic cancer model is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)OA: greenTopics (36)IDs (PubMed, OpenAlex)SDGs (2)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Patrick B. Schwartz ORCID,Noah D. Carrillo ORCID,Kristina A. Matkowsky,Manabu Nukaya ORCID,Christopher A. Bradfield ORCID

Live enrichment

PubMed:36778364 OpenAlex:https://openalex.org/W4319232944

National Institutes of Health

Grant: 5R35ES028377-02

The PAS Sensor Family and Human Health

National Institutes of Health

Grant: 5T32ES007015-35

Molecular & Environmental Toxicology Pre-& Postdoctoral Training Program

National Institutes of Health

Grant: 5P30CA014520-18

CANCER CENTER SUPPORT

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/02/03/2023.02.01.526625.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.01.526625

repositoryhttps://doi.org/10.1101/2023.02.01.526625

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36778364

Fields of Study

Toxic Organic Pollutants ImpactEicosanoids and Hypertension PharmacologyWater Treatment and Disinfection0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

KRASAryl hydrocarbon receptorInflammationCancer researchImmune systemTumor microenvironmentPancreatic cancerPathogenesisBiologyCD8Tumor initiationCancerImmunologyCarcinogenesisTranscription factorBiochemistryGeneticsGeneMice, KnockoutBasic Helix-Loop-Helix ProteinsArticleMice, Inbred C57BLPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)MiceDisease Models, AnimalReceptors, Aryl HydrocarbonMutationAnimalsCarcinoma, Pancreatic Ductal

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being