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Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.14.528376Source: DataRank Database

Human gene regulatory evolution is driven by the divergence of regulatory element function in both cis and trans is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0.

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)OA: greenTopics (29)IDs (PubMed, OpenAlex)SDGs (1)

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Authors (4)

Sarah Fong ORCID,John A. Capra ORCID,Emily Hodges ORCID,Tyler Hansen ORCID

Live enrichment

PubMed:36824965 OpenAlex:https://openalex.org/W4320917732

National Institutes of Health

Grant: 5R01GM147078-02

Decoding genome function with DNA methylation and human phenome data

National Institutes of Health

Grant: 5R35GM127087-03

The Evolution of Gene Regulation and Human Disease

National Institutes of Health

Grant: 1T32GM080178-01

Training Program on Genetic Variation and Human Phenotypes

NIGMS NIH HHS

Grant: R01 GM147078

NIGMS NIH HHS

Grant: R35 GM127087

NIGMS NIH HHS

Grant: T32 GM080178

greenLicense: cc-by-nc-nd

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/02/15/2023.02.14.528376.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.14.528376

repositoryhttps://doi.org/10.1101/2023.02.14.528376

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36824965

Fields of Study

Genomics and Chromatin DynamicsRNA Research and SplicingCRISPR and Genetic Engineering0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

Trans-actingBiologyRegulatory sequenceGeneDivergence (linguistics)Function (biology)GeneticsTranscription factorRegulator geneCis-regulatory moduleRegulation of gene expressionGene regulatory networkEvolutionary biologyGene expressionEnhancerArticleComparative GenomicsDNA Regulatory ElementsFunctional GenomicsGene RegulationHuman EvolutionLymphoblastoid Cell LinesMassively Parallel Reporter Assays

Sustainable Development Goals

SDG 0: Life in Land