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Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.14.528563Source: DataRank Database

Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy is a research paper published in bioRxiv (Cold Spring Harbor Laboratory) (2023). On theSindex it has a DataRank of 0. It has been cited 4 times.

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Enrichment:Funding (3 grants)OA: greenTopics (35)IDs (PubMed, OpenAlex)SDGs (2)

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Authors (12)

Elizabeth Phillips ORCID,Zhijiu Zhong ORCID,Nadan Wang ORCID,Jasmine Saunders ORCID,David Mothy ORCID

Live enrichment

PubMed:36824975 OpenAlex:https://openalex.org/W4320919881

National Institutes of Health

Grant: 5R01HL150019-04

Cell type-specific function of LMNA during myocardial stress in the development of cardiomyopathy

National Institutes of Health

Grant: 1S10OD010408-01

Vevo 2100 ultrasound scanner

National Institutes of Health

Grant: 5R00HL118163-04

Dusp4 in the pathogenesis of LMNA cardiomyopathy

greenLicense: http://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

repositoryhttps://www.biorxiv.org/content/biorxiv/early/2023/06/07/2023.02.14.528563.full.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1101/2023.02.14.528563

repositoryhttps://doi.org/10.1101/2023.02.14.528563

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36824975

Fields of Study

Nuclear Structure and FunctionRNA Research and SplicingEndoplasmic Reticulum Stress and Disease0301 basic medicine0303 health sciences03 medical and health sciences

Keywords

LMNALaminCardiomyopathyCell biologyBiologyAutophagyDownregulation and upregulationNuclear laminaCancer researchHeart failureMedicineTranscription factorGeneticsInternal medicineNuclear proteinGeneNucleusMice, KnockoutNuclear EnvelopeGolgi ApparatusLamin Type AEndoplasmic Reticulum StressMiceDisease Models, AnimalStress, PhysiologicalAnimalsMyocytes, CardiacBiomedicine and Life SciencesCardiomyopathies

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being